David Sinclair: Living to 120 and beyond | ABC Conversations Podcast

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ABC Australia

ABC Australia

Рік тому

David Sinclair joins Richard Fidler on ABC Conversations
Discover more from ABC Conversations on the ABC listen app
ab.co/ABClisten
David Sinclair OAM is an Australian biologist based at Harvard University who is leading scientific fight against the inevitability of aging.
Dr Sinclair believes aging is a disease, and we can find a cure for it.
In the process, his lab has cured blindness in mice and has created tiny little brains out of human stem cells, which look like “little flesh-coloured peas”.
Further information | ab.co/Conversations
Lifespan is published by HarperCollins
Credits
Richard Fidler, Presenter
Carmel Rooney, Executive Producer
Meggie Morris, Producer
Broadcast 28 Feb 2022
#podcast #conversations
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This is an official Australian Broadcasting Corporation UKposts channel. Contributions may be removed if they violate ABC's Online Conditions of Use www.abc.net.au/conditions.htm (Section 3).

КОМЕНТАРІ: 133
@grantjones8690
@grantjones8690 Рік тому
82 now; two years I was in pretty good shape but starting to go downhill. Lifelong weight training but low fat, high sugar, alcohol, high carb, constant eating was taking it’s toll. Gradually switched to low carb, hi fat, time restricted eating, supplements. My body is undergoing a healing process, where everything is improving. I think that one is never too old to start significant rejuvenation.
@LK-pc4sq
@LK-pc4sq Рік тому
Take a look at NMN and NAD supplements.
@user-pi2oo2jh5d
@user-pi2oo2jh5d 8 місяців тому
, 2:53
@malsherbeeny
@malsherbeeny Рік тому
You're building a real arc for humanity. Thank you Noah.. I mean David. I love your work, and you've truly become my life coach and mentor since I watched your videos on UKposts 6 months ago. May nature yield and bow to your clever mind.
@sleepsmartsmashstress740
@sleepsmartsmashstress740 Рік тому
You mentione Noah and David what about Moses and Goliath. Let us get the full cast before we make the movie.
@psychobabbler
@psychobabbler Рік тому
Possibly the greatest Australian of all time
@LK-pc4sq
@LK-pc4sq Рік тому
David is American
@jozette-pierce
@jozette-pierce 2 місяці тому
Yikes, guys, he's both. We both get credit, along with his mom and dad.
@starbettypink
@starbettypink Рік тому
this is awesome ❤
@nimfabangay7318
@nimfabangay7318 Рік тому
Very interesting....ty❤
@Elasworld71
@Elasworld71 Рік тому
Wow this is so interesting.
@tomu4725
@tomu4725 Рік тому
Good video. Others like aubrey de grey think we have a 50% chance to extend our lives by 1 additional year each year within 15 years. Once at that point, we should pretty much live indefinitely unless we get hit by a car or something like that.
@sleepsmartsmashstress740
@sleepsmartsmashstress740 Рік тому
But the reality is we are going the other way, life expectancy of Americans keeps shrinking
@secretname2670
@secretname2670 Рік тому
@@sleepsmartsmashstress740 not my problem they keep eating literal fried trash and drinking lead poisoned water
@Jessica-kk1cz
@Jessica-kk1cz Рік тому
Ugh. I want video. I don’t know why I want video, but I want video. These breakthroughs have been absolutely fascinating. I’ve been tracking Sinclair and similar scientists for 3 years now. Another good channel to watch is Modern Healthspan. Richard brings on all top scientists. Ignore the bransfieild guy - but everyone else has been excellent.
@moseshorowitz4345
@moseshorowitz4345 11 місяців тому
Reminds me of an episode of The X Files, where a doctor treated ageing as an opportunistic disease. When Mulder and Scully meet him in the 1990s he looks identical to his pictures from the 1950s.
@Elasworld71
@Elasworld71 Рік тому
I wish I could look over your shoulder while you do all tge amazing stuff you do.
@andreasneeb7448
@andreasneeb7448 Рік тому
In the Interview Dr. Sinclair say that there will be a human study for glaukoma in 18 month. Could you please provide a contact to be part of this?
@rhuyisia8163
@rhuyisia8163 Рік тому
I have nothing against looking young and living like forever! My problem is financial constraints! 😭
@Robin_P_Patriot
@Robin_P_Patriot Рік тому
If you are healthy you don’t have to retire 😂
@I8l
@I8l Рік тому
@@Robin_P_Patriot if u are poor u probably cant afford the treatments that will allow you to live to 120
@janemuses3031
@janemuses3031 Рік тому
I agree with Dr Sinclair's viewpoint, which is better accepted in Asian countries, that the wisdom that comes from having lived life is to be valued. Ageism, especially in western culture perpetuates the belief that one is "over the hill" past a certain age. Why should age be a factor if one is fit, sound of mind, and can still be a productive member of society? With the diminishing birth rates in developed countries, this outdated mindset puts undue strain on the younger generation to support the older. I think it's a wonderful goal to try to live to 120, regardless of whether you actually achieve that because think about how much more you can achieve in that time. Instead of thinking you need to retire and be "put to pasture", you could be planning to start a totally new career if you choose to do so, go back to school or explore many new avenues of endeavor. This second stage in life, where you are past the responsibility of bringing up children, can be focused on self-development and trodding down the paths less traveled.
@metaphysicalArtist
@metaphysicalArtist Рік тому
@34:00 what is the present thereapy for Macular degeneration can NMN help stop or reverse the issue
@LindsayMach
@LindsayMach Рік тому
I'd be curious Dr. Sinclair's thoughts on earthing / grounding and the potential abilities that may have to health / anti-age the body.
@David-sq2en
@David-sq2en Рік тому
what is that?
@BJ-fu4zy
@BJ-fu4zy Рік тому
@@David-sq2enbare feet on earth
@tube2211ification
@tube2211ification Рік тому
This interview was back in February how about putting it on UKposts when it’s put on the abc website.
@SquatFull
@SquatFull 10 місяців тому
I would appreciate a response to Dr. Charles Brenner's Article "Sirtuins are not conserved longevity genes" Life Metabolism, Volume 1, Issue 2, October 2022, Pages 122-133.
@jlvandat69
@jlvandat69 Рік тому
👍👍Excellent interview. Thank you gentlemen. I wonder...... when it comes to speculating how many more years of life a certain generation may have as a result of current and future medical breakthroughs and improved lifestyles, could it be possible we're grossly UNDERESTIMATING those numbers? Said differently, perhaps the developments will progress at a much faster rate than most expect, causing humans who are currently in their 50's to potentially live to be 130+? Asking for a friend.......
@alex_rogan
@alex_rogan Рік тому
Take a look into what hes trying to do with NMN and his proprietary blend and how he’s attempting to control the supply now that it’s been banned.
@monag.769
@monag.769 Рік тому
Nobody tries to control anything here
@sandybayes
@sandybayes 9 місяців тому
I just bought some. Not banned.
@drblaneyphysics
@drblaneyphysics Рік тому
How can you retrieve lost information? Did I miss where the original info was saved? e.g...Which cell has the info and in what form. thank you [anyone] if you know.
@BlackMamba-lt8oe
@BlackMamba-lt8oe Рік тому
No cell
@deanmindock3680
@deanmindock3680 Рік тому
He did say that there is a copy that contains all the original information but I didn't catch its name/location. He said that that copy was a "big deal". AFAIK, it must stored within a cell, likely in the nuclease.
@I8l
@I8l Рік тому
u could take a blood sample and freeze it just incase you want younger dna available if it ever matters. maybe it will maybe it wont
@mirandapillsbury7885
@mirandapillsbury7885 Рік тому
it's exiting but it is also sad because I do believe this will happen but every born before the 2000s will probably not live long enough to enjoy these breakthroughs. I'm a 1995 kid...I'm probably going to miss it by a hair....oh well
@sunmoon-84
@sunmoon-84 Рік тому
A question in regard to fasting or time restricted feeding. We are told for example we need 4700mg of potassium per day, that is just one of many recommendations to keep our body running efficiently. With time restricted feeding how do we make sure we meet those goals? Is it possible that our body doesn't actually run on a 24 hour clock and we don't need this daily? Or does digestion itself dictate our 'daily' nutritional requirements. I'm confused, any comments?
@Layoorah
@Layoorah Рік тому
When doing long fast you should be consuming electrolytes. It depends on you and your body how long you can safely go without potassium but if you are going to be doing a fast of 24+ hours or exercising while fasting 18+ hours I highly recommend electrolytes. You can find zero calorie fasting electrolytes online. Be careful choosing, check the labels.
@defiscanner1927
@defiscanner1927 Рік тому
You need a half thumb sized piece of ginger, 2 kiwis and 1-2 lemons per day + green tea and black tea + a table spoon of honey. Also a nice salad with beetroot. That will keep you healthy
@marynayna6327
@marynayna6327 Рік тому
Get onto UKposts and start educating yourself on all the info on nutrition and fasting,I’ve been on a ketogenic lifestyle of eating now for over a year have lost 40 Kgs at 72 feel better than I have for decades,I also only eat once a day at lunch time,have lost my carb addiction and best of all feel happy. I recommend listening to Australian Dr Paul Mason, Sten Ekberg, Dr Becky Gillaspy, Dr Ken Barry.
@carolinelewis952
@carolinelewis952 Рік тому
I use Lugals potassium drops and electrolyte drops.
@tedwalford7615
@tedwalford7615 Рік тому
Regarding time-restricted eating, I'd think that dinner would be the meal to skip, not breakfast!
@jdacasin
@jdacasin Рік тому
I believe it
@sleepsmartsmashstress740
@sleepsmartsmashstress740 Рік тому
A more accurate manner of stating what is being referred to as slowing the aging or putting the foot on the brake paddle is to take the foot of the accelerator. All that is needed is to stop the pro-death habits of gluttony, being sedentary, partying, smoking, binge drinking, street drugs the list is long and known to all of us but who is stopping.
@GOBEF3
@GOBEF3 Рік тому
Once Sinclair hits 100 we be delighted to consider his thoughts on his next 20 ... not a minute before.
@enkibumbu
@enkibumbu Рік тому
Cosmic irony would never allow it.
@zegikniet9999
@zegikniet9999 Рік тому
what aboud taking nmn?
@Journeyman-Fixit
@Journeyman-Fixit Рік тому
I started using IF in 2019, I feel so much better doing it I can't ever go back to the old three meals a day again.
@jeremywvarietyofviewpoints3104
@jeremywvarietyofviewpoints3104 Рік тому
It's interesting how he eats less but his body adapts to not feel hungry.
@jdacasin
@jdacasin Рік тому
Im only on Dr sinclair style just 3 years ago
@jdacasin
@jdacasin Рік тому
I am 59 years old now
@darshuetube
@darshuetube Рік тому
What do you think about the work of Dr Michael Levin? Bioelectric?
@gloriagolemboski4515
@gloriagolemboski4515 Рік тому
What’s your opinion with Strotium and calcium.
@MissChatterton
@MissChatterton Рік тому
What an amazing and interesting interview gosh I’m going to have to listen to it again so much to take in!
@burnoutminion
@burnoutminion Рік тому
The thought of living to 80 makes me feel instantly depressed
@yodidabhutia7935
@yodidabhutia7935 Рік тому
👍
@olivergeoffreyblakely7623
@olivergeoffreyblakely7623 Рік тому
If you listen to other experts.. on the subject, they have said NAD or NMN the supplement is nowhere close to progressive exercise, primarily V02 Max.
@Dan-uf2vh
@Dan-uf2vh Рік тому
I was falling into lethargy a year ago even with over a decade of exercise. NMN turned that around bigtime. It depends on what is going on with the metabolism and how much each person needs to boost NAD+ chain. I suppose mine was very poor.
@neerajmehta4993
@neerajmehta4993 Рік тому
@@Dan-uf2vh do you recommend this to a person with less than normal health but no major health issues. In other words, a person either 6.7 A1C or 150/80 BP etc.
@squamish4244
@squamish4244 Рік тому
I did NAD intravenously (they really need to study this method of delivery, because it is much more bioavailable than as a supplement) for addiction problems, and it had a huge effect on my joint and muscle pain and, for the next few weeks, my stamina and flexibility. Really remarkable. And I noticed this change at age 40, so for someone older whose natural levels are much lower than mine...
@squamish4244
@squamish4244 Рік тому
@@neerajmehta4993 Yes. See my comment.
@lisagothier7477
@lisagothier7477 Рік тому
@@Dan-uf2vh what nmn do you take?
@nmambuehnawe3324
@nmambuehnawe3324 Рік тому
Living to 120yrs is normal. Can the scientists increase longitivity to 300yrs??
@jimsmart6940
@jimsmart6940 Рік тому
If they can get you to 120, technology will be such that you can probably get to 300 or whatever age you want
@megabaneen8057
@megabaneen8057 Рік тому
I want 🍬 candy
@enkibumbu
@enkibumbu Рік тому
Yes, but it costs 2 billion dollars.
@greywolf850
@greywolf850 Рік тому
Show me the 120 guy that followed this protocol… meanwhile we had a 114 year old AZ man who loved that long just eating biblical foods like honey, cinnamon, real fruit and vegetables, olive oil, garlic … research already exists on how live into your 100s
@monag.769
@monag.769 Рік тому
So with Davids discoveries we will live much longer😊
@secretname2670
@secretname2670 Рік тому
But david also advises on eating normal, vegetarian leaning diet with fish and some olive oil , honey and exercise. Bible is right about a lot of things for some reason. I don't know why or how but a lot of christian basis for life has impressively good results. Don't overeat, don't be gluttonous, don't feel anger or hatred, try to be compassionate, work fairly but don't burn yourself out for no reason are all great life advice.
@enkibumbu
@enkibumbu Рік тому
Guy's an investor and director in the companies who make the supplements he recommends.
@sandybayes
@sandybayes 9 місяців тому
Not when he begin taking the regime.
@phillebedev4300
@phillebedev4300 Рік тому
The universe is the mind and we are all one and spiritually immortal. To be biologically immortal being perpetually healthy and youthful should be the easiest thing to do. Just know that it is possible.
@squamish4244
@squamish4244 Рік тому
If we realize #1, we don't need #2. Although living long enough to guarantee that your spiritual practices pay off to realize #1 would be nice :)
@sleepsmartsmashstress740
@sleepsmartsmashstress740 Рік тому
Were longevity to become a public reality then global poverty would revert the trend and people would begin to die sooner from homelessness starvation lack of healthcare etc., so the dream of longevity is only for the superwealthy and those with a doctorate etc. and mostly a fantasy.
@dapawap
@dapawap Рік тому
I will make it to 120 & have 120 years of problems!…..😢😅😊
@ranghashalatr142
@ranghashalatr142 Рік тому
Some people say live life forever you say live 120 what about on news
@tarannumrahman5522
@tarannumrahman5522 Рік тому
How to stay young like 20 years old body for as long as we live
@iguanaamphibioustruck7352
@iguanaamphibioustruck7352 Рік тому
There is no place in our society for over 80. What do we do with another 40 years. Iguana (87)
@erikacsizmadia2863
@erikacsizmadia2863 Рік тому
What do you WANT to do?
@groia2104
@groia2104 Рік тому
Good point though…
@deanmindock3680
@deanmindock3680 Рік тому
You have to motivate yourself. Do the things that interest you and make you feel happy and content.
@asmrclipps
@asmrclipps Рік тому
Immortal humans have walked the earth for centuries. Didn't you know?
@David-sq2en
@David-sq2en Рік тому
how to become one?
@marynguyen9365
@marynguyen9365 Рік тому
Living healthy is Nice. Living to 120 to see all people around you and your loved ones disappear? I don't want to live alone . Go along with nature. Sickness is a concern, Not the length of time to live
@jeremywvarietyofviewpoints3104
@jeremywvarietyofviewpoints3104 Рік тому
What if others live long too?
@David-sq2en
@David-sq2en Рік тому
I'm 40 and already see this happened... so...
@ameliaramos5225
@ameliaramos5225 Рік тому
Sorry..but why that so vague definition of deseasses? Thought that health was the constant on.our lives and illness was the exceptional events...
@heyyou9839
@heyyou9839 9 місяців тому
He’s got his strengths but take him with a grain of salt - see his resveratrol controversy
@jmd1743
@jmd1743 Рік тому
It would be pretty revolutionary for women who desire both a family and career. If you could live to the age of 300 then then what would be the problem with having kids and then REALLY focusing on your schooling in your mid 40s once the kids move out? As a women you'll feel accomplished with the whole child business and by the time you start schooling your eggs would have begun to run out. Women would be able to have their cake & eat it all.
@dapawap
@dapawap Рік тому
We don’t need any more kids in this world! The world is way way over populated!
@jimsmart6940
@jimsmart6940 Рік тому
If we can live to 300, technology will probably be there for men to have kids as well.
@lekiwatcher
@lekiwatcher Рік тому
nmn banned, why David, WHY?
@alex_rogan
@alex_rogan Рік тому
So he can then sell his proprietary blend
@kantoquad
@kantoquad Рік тому
@@alex_rogan Had such respect for the man. He talked like he cared, but now only a few who will be able to afford his version many only be able to afford it. He seems to only care about the rich, and only if they pay me
@I8l
@I8l Рік тому
@@kantoquad if you really think about it.. its a good thing. Why have chinese companies make money off of nmn. He can pump the price a little and its just that much more capital to be re-invested in research.
@Alice_Walker
@Alice_Walker Рік тому
Cool story but how the heck do I fund an extra twenty years of retirement???
@dapawap
@dapawap Рік тому
And all those extra years of problems & challenges! No one escapes them!
@David-sq2en
@David-sq2en Рік тому
maybe learn how to save and then how to invest?
@FreemonSandlewould
@FreemonSandlewould Рік тому
Geebus this was slooooooooow
@johnnyq4260
@johnnyq4260 Рік тому
The onus is on him to live to 120 to prove his theories.
@David-sq2en
@David-sq2en Рік тому
what if... he already did?
@monag.769
@monag.769 Рік тому
I prefer to follow his example. If he‘s right l don‘t want to waste time waiting for it to happen;-)
@yavuzyazir9132
@yavuzyazir9132 Рік тому
i will give an example to mr. Sinclair from totally different and negative perspective so that i hope he undwerstands what his work may do to the world. Dear David, imagine there is one nice hospital in a particular place which can hold and cure up to 1000 patients. and suddenylly, you start adding more pesticides and chemicals to the soil, where that community is fed from and as a result, number of patients start significantlly increase... now tell me Mr. Sinclair, suppose you cant extend the existing hospital, how do you think that hospital will respond to that situation? Meaning, how our already depleted and contaminated soil with lots of chemicals can produce enough and clean food if you extend avarege Joe's life 5-7 years resulting rapid increase in world population?
@L.J.01
@L.J.01 Рік тому
Saying cancer will kill everyone if they live long enough is based on what exactly? 😂
@dapawap
@dapawap Рік тому
Valder Longo says if we stop the IGF1 mostly in animal products we won’t get various diseases & cancers 🥳🥳🥳
@mcnchse
@mcnchse Рік тому
I want to live to 120 in my 20 year old body, not old, frail, deteriorating, and can't go anywhere.
@fullerexplanations7872
@fullerexplanations7872 Рік тому
I think Elon Musk needs to get involved with this also at some level. NeuraLink can help in some capacity but there are other avenues he can help boost to help get these developments faster
@David-sq2en
@David-sq2en Рік тому
please no
@sandybayes
@sandybayes 9 місяців тому
Musk has said he doesn't want to live longer.
@RJ-is9ko
@RJ-is9ko Рік тому
Better have the retirement funds for that
@David-sq2en
@David-sq2en Рік тому
you can use time to make money... that is never the problem. the problem have always being to use the money to buy time.
@malcolmwhitehead7225
@malcolmwhitehead7225 Рік тому
What about population growth. Do you cut down even stop breeding for years? MW
@David-sq2en
@David-sq2en Рік тому
sadistically speaking yes. the trend is that as people live longer they have less kids.
@farinshore8900
@farinshore8900 Рік тому
No thank you.
@ebrelus7687
@ebrelus7687 Рік тому
You won't reach 120 with pharmacology while not eating human species proper diet with meat, eggs, fish and natural milk/dairy. Ancient Etiopians would laugh him out.
@sandybayes
@sandybayes 9 місяців тому
Please read some recent studies.
@squamish4244
@squamish4244 Рік тому
And those medieval people wore out and died younger due to malnutrition and gruelling hard work. We should only get 'kind of' medieval :P
@AbdulRehman-ch5cp
@AbdulRehman-ch5cp Рік тому
i want to connect to ABC Australia (team) on email
@MrCharlesdick
@MrCharlesdick Рік тому
If you use a transgene expressing those 3 Yamanaka factors, and include telomerase reverse transccriptase, might the result be even more better?
@DeSoccerRefMan
@DeSoccerRefMan 10 місяців тому
telomerase reverse transccriptase?
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