That Moore catch down the sideline gotta be one of the better catches of the year, as well as the TD to Hopkins on the defenders head.

If Trey Lance wants a long career in the NFL he's gonna need to slide more or not run as much. He took way too much hits just in this game that his mom had to look away.

As a niners fan, I’m happy for Cardinals fans. I know how it feels, the excitement of staying undefeated well into the season, reminds me of our 2019 season. Best of luck to you guys.

Rondale Moore has SERIOUS skills.

AZ lost these kind of games all the time last year. This is a big win for the Cards no matter what any of you guys say.

Rondale Moore's catch was insane!

How smart does Watt look right now? Everybody saying AZ wasn't going to be a real contender. They're looking ok so far.

Every since we got d-hop so much has changed. I know he is not the only reason but man his hands and ability are insane. Way to keep fighting Cardinals, we are really fighting for it this season!

Defensive game between 2 division rivals. Every game won’t be us scoring 30+ in a blowout win. All that matters in the end is the W. GG Niners, onto the Browns.

That pass and catch from Murray to Hopkins out of the end zone was moneyyy. Murray’s accuracy has gotten a lot better since his rookie year. Definitely helps with the players he has now

Cardinals are looking good like they did in 2015. Hope they keep this up and stay healthy they’ll have a chance to get to the Super Bowl.

I'm actually glad to see that we can manage to win a game even when our offense struggles. Phenomenal showing by the whole defense today.

Arizona is so dynamic this year and can win in many different ways. Whether its an offensive shootout or a defensive onslaught. Its a beautiful thing to see

Everyone calling this a bad win for AZ. This was actually a great win for the Cardinals. The Niners still have a great pass rush and are very physical at the line, and you have to give them credit for the way they played today. These are the types of games where even when AZ was good in previous seasons, they would have typically lost. Now they are capable of matching the level of physicality of their opponent in these nasty, super physical defensive slugfests. It’s going to be awfully tough to beat the Cardinals this season

There is nobody in the NFC I would like to see more going to the playoffs and SuperBowl than the Cardinals, and I am a Niners fan. Much respect for the team from the Desert.

This is one of these rare times when it feels good to be a Cardinals fan. Murray and D-Hop did their thing and defense stepped up big on some key plays. Amazing catch by Moore. At the same time Kyle made some bad calls and penalties killed some great plays for the Niners. GG guys. One week at time, onto Cleveland.

Prayers to my boy max, ive had the same injury. Get well soon! Who was a fan when we went 3-13? cos i was.

I expected the 49ers to lose this game 30-9 but amazingly they kept this game close even after shooting themselves in the foot with all those failed 4th down conversions thanks to bad play calling. GG Cardinals.

Lance is good on his feet but he's got to be careful running into walls if DBs. Like his gusto but hope he can continue to improve and succeed

What a game by JJ WATT

Bruh that toe tap catch by Moore is Godly

The big difference so far between this season and the last is that the Cards are making the clutch plays on both sides of the ball - they're not only making the 3rd-and-longs when they have to but stopping are their opponents when they have to as well. How many times did they halt the 49ers on 4th down? I'm not celebrating yet - this team has collapsed in the second half of the season before - but for now they look pretty fierce.

The Cardinals looked amazing out there, San Fran looked like they weren’t doing too bad either other than shooting themselves so many times with all those damn penalties

5-0 I been a cards fan my whole life and I’m now finally seeing the light at the end of the tunnel for this team

Every niner fan out there we should be proud of our team our defense played amazing against the best team offense in the league held them to 17 points and trey lance just needs more time to develop and get more experience on field 💯 love my niners man 🔥🤟🏼

Fun fact: the Cardinals have the best record in the NFL

Prayers up for Maxx Williams, on other replays, that hit on his knee looked bad, probably blown knee. He was doing great this year too, our version of Gronk in many ways.

Kyle needs to utilize lance in better plays that fits his style. One last thing is we are hurting ourselves too much with penalties on offense, trey can’t develop with a bunch of holding penalties. Overall I thought that we should clean up play calling. Hopefully we can bounce back against the colts after the bye week. GG cardinals

Besides the monsoon game in 2019. This is lowest scoring team total for the 49ers since 2018 with Nick Mullens with 10 points.

I am so happy the Arizona Cardinals are 5-0. Great things are happening in the desert 🏈🌵

As a Seattle fan I love that the Cardinals are looking good, hopefully at the end of this season we can say every team in the NFC West has a trophy.

POV: You have dhop in fantasy and was getting frustrated till the last couple of minutes

Absolutely tho this was such a big W for the Cards , no matter what anyone says , like damn I can’t believe they’re still the only NFL unbeaten team left .. 5-0 start since 1974

Ugly win is still a win! Good game 49ers..yall played some good Defense!! See you in a month! GO CARDINALS!!!

Kyler to D Hop was insane, JJ Watt had a fire game, 5-0 let's go AZ 🔥🔥

The game I like are close ones, with good offense and defense. That was how that game was.

I’m honestly getting 2015 cardinal vibes from this team right now let’s see if they can meet the expectations

I know it wasn't the best performance by murray but he is still looking like the front runner for the MVP go cards, even though I am a cowboys fan.

One of those games where the 2019-2020 cards would’ve lost. What a game

There were a lot of flags and why tf are the 49ers running plays like he’s Lamar Jackson

Wow. 5-0. I wouldn’t be surprised if they make it to the NFC Championship.

11:45 - Hopkins TD. There is absolutely nothing about the defense and coverage on Hopkins to tell Murray to throw that ball. That was 100% i’m throwing to my best player and we’ll see who wins. K1 and Hop are ridiculous.

Watching that 4th down goal line stop in person was insane!! Its a credit to this defense they never give up.

Rondale Moore is something special

O MVP D-Hop, D MVP JJ. Thank you, Houston.

Kyler Murray and the Arizona Cardinals are having a good year in the 2021-2022 season!!! Kyler Murray and the Arizona Cardinals are going to playoffs, if they keep this up!!! Let's go Cardinals!!! Rise up sea red!!! How bout them birds in Arizona!!!

Isiah Simmons hit on Lance at the GL on 4th down fired me up to no end. He unselfishly gave up his body and jumped on the grenade. And blew up Lance.. Changed the game flow. Let's Go!!! 5-0.

5-0 feeling YES! YES! YES! Vance Joseph is Defense was the factor today!

Cardinals are definitely for real this season

Kyler Murray and the cardinals are for real.

Kyler Murray is making a beautiful work in this season. Congratulations, Kyler and the full Cardinals team for the 5-0 record!!! 👏👏👏

This was A Certified "Cardinals" Classic

Cardinals defense stepped up without their best cb Byron Murphy and Murray to d hop came when it matterd! Cards are a superbowl threat!

we make good addition this year, james connor, moore, aj green and of course finally a kicker.. go sea red.. fans from indonesia

It's getting lonelier at the top. AZ is getting it done this year!!!

The Cardinals are definitely the team to beat in the NFC right now.

AZ’s black jerseys are sick

Zach Allen is really an unsung hero on the Defense. Hes gotten so much better since his rookie season

The only thing I heard the most is “Holding… offense number…” for SF lol

Cardinals corner backs were all hurt except for Robert Alford.

Cardinals the most dangerous team in the NFL rn, them boys some DOGS 🔥

Do ya have any idea how good kyler is??? The dude is red dotting receivers who are 5’7.. whats the main thing you hear about prototypes Julio Dk big hands big catch radius. Murray is diming a guy 5’7 that window is super small its not alotta qb’s out there that can even throw in a window like that.. it’s insane and he’s doing this at 5’9 himself.. people ur witnessing something great and im not even a cards fan.. this is special..

And they said Kyler Murray is too small to play football 🤣

Baker has an interception not even a minute into the highlight? Yep sounds about right.

That collision at the goal line I’m glad they all got up from that wow

The only reason our offense stalled for most of the 2nd half was because of losing Maxx Williams and Rodney Hudson to injuries. Luckily, our defense gave up the yards but not the critical plays. GG 'Niners. This is the best defense I've seen from this team since 2015.

Nice to see JJ Watt look like the old JJ of Texans, a lot of pressures . Great job !😉👍

Arizona we started off strong in the beginning I thought it was going to be a More offensive scoring game. Max getting hurt really killed are momentum and energy that’s when we started to mess up offensively and Hudson got injured and kyler got hit in his bicep was a bit injured and most of the game after we started to throw screens and check downs. Overall defense stepped up and looking for our team to get healthy this week upcoming week and look like the same explosive team as last week good win tho !

GGs 49ers Lance gonna be real threat next year or two. My cards barley made it thru by the skin of our teeth. Man some casualties in this division battle. Hope these guys recover soon.

rondale moore is incredible! best draft pick out of any of the picks by far... i don't care if he plays receiver the kid is amazing man.. rookie of the year locked up already. for trey lance having his 1st start in a big game like this i can't complain... he had some nice throws and showed he has heart. i would like to continue to see him out there for the rest of the year. he will only get better the more he plays and we all know next year he will be the guy so why not give him the time NOW?

That Murray to Hopkins TD at the end was poetic justice. That 9ers defense mocked him the drive before that, then the clutch TD pass over Norman.

Cardinals are on fire 🔥

We could’ve won, just like Seattle and the packer game. But again, Kyle shanahan with some atrocious play calling. His time is ticking in sf if he continues dumb ass offensive calls. Not just that, but letting trey put himself at risk on some of those run plays pissed me off. Our defense is the only thing keeping us in games yet our offense lets us down 😞

I don't know what it is (tacky gloves, superglue) but level of wide receiver play has been off the charts this year. I've never seen so many spectacular catches in my life.

Gotta feel good for James Connor. He works his tail off and now seeing success with the Cards. I watched him at Pitt and also the Steelers. Go James!!

Proud of my Cardinals team. We had some sloppy plays that the 49ers exploited but a win is a win. Now off to Cleveland we go.

That TD pass to Hopkins was a thing of beauty.

4:20 Mark Sanchez reaction was all of us. Maxx Williams we love yah man can't wait to see you next year!

I said it at the beginning of the year, the Cards are the best team this year! Until now, they've shown it every time🎉

J.J. Watt played like the Defensive Player of the Year during his years in Houston.

Well the offense didn't really click this week like they did last week. But the defense really did their job.

Rival games are one the hardest games to win, they know each other to well.

I don't mind 9er fans in Glendale, they generate the City a lot of revenue, and it's always great to see 9er fans at State Farms Stadium and taking a massive L. I'm From Phoenix Indian School and 19 ave!! GO RED SEA!!

cardinals out here making history

Trey lance should start the rest of the year he needs playing time. Not a superbowl team, probably not a playoff team either but hard fought game this week.

That block on Lance in the endzone in the 2nd. I felt that in my soul.

This is proving to be a special season. 5-0 for the first time since 1974. Still aways to go but it's an amazing start.

The reporter during the game said that Jimmy should be able to return after the bye week which is great news.

Go cardinals, they are going places. They need their first super bowl win.

I love both teams, that boy Murray keeps on getting better and better each game. Lance is still a rookie, that’s how Murray used to play last season. Hopefully Lance will soon get better.

Omg that hit on Lance at 3:45 could wake up the dead, i cant believe he wasnt injured

I’m just happy Lance is out there getting the experience he needs. It had to happen eventually and if it means giving up this season for much success in the future for him and the team (like Josh Allen and the Bills) then I’m in. Stay Faithful faithfuls!!!

Murray and the cards move up to 5-0, the first time they’ve ever achieved that in Arizona. This puts Arizona in prime playoff position already, even if they go .500 the rest of the year they’ll finish at 11-6.

Loved how Samuel didn't just step out of bounds but delivered a blow to the defender 1st!

What a throw and catch man. The throw was CRAZY!

Niners played tough ngl!

49ers couldn’t go a drive without a holding penalty.

Murray and hopkins are so good together. Fun to watch.

Love how in synch the handshake was at the end .

Browns vs Cardinals should be SNF Not Steelers and Seahawks