A very happy birthday to you!

No Vodka?

Congratulations. Live long and prosper!

Happy birthday you . What all supplements you have been taking ?

Food and walking are the keys to health.

and he looks exactly the same... imagine

I agree!

Go back! I want to be monke!

david pushes covID govt narrative

😆

Excellent Greg!! That boils it down to a usable life style without being confused with so many messages, and messengers.

Avoid carbs is bullshit. The biggest example is that the longest living people on earth (living in the blue zones) eat many carbs. We have to distinguish between Refined sugar (which you should definitely avoid) and complex carbohydrates, that the body needs to digest, these carbs have low glycemic index. Many healthy foods like whole grains, legumes, fruits, and even vegetables have a big amount carbs, and to avoid carbs, we would have to avoid those foods, and essentially avoid important nutrients like vitamins, minerals, and disease-fighting phytochemicals. I highly recommend a video called: „Deconstructing the Paleo Diet“, that talk touches on the carb myth.

@@SchgurmTewehr Look at Asian population 50 years ago...Especially India they lived on so called low GI carbs... I think I don't have to elaborate more on that... Carbs are futile

@@SchgurmTewehr It’s a pity the science disagrees with you. Carbs are totally unnecessary and too much too often leads you to insulin resistance, which leads to metabolic disease.

@@snowflake5204 No, you shouldn’t elaborate from epidemiology. I just gave an example, but we shouldn’t elaborate from epidemiology - it just gives us a clue what to look at.

Where can you get this?

@@ElonizuMuskamoto I get it from Amazon. But in my experience, I don't feel much effect unless I exercise. When I take NMN, the more I exercise, the more I want to exercise.

How did you found MNN

@@lourdesmartin6602 I searched on Amazon. A lot of brands were too expensive but the Livemax brand in multiple bottle packages came out to a dollar a day or less.

What is mnm?

very good experience. great remedy for asthma.

@@R.R.Brahma ….it's all for body integrity in general.

Whaaa? Good for you.

How could you at this young age be so wiser? Fews people are awake enough to even see they have body to take care of, just leave it para some known dr out there.

Wow. I am impressed, really. You're 11 then and yet you've done fasting?! Good for you👏👏

hahaaa good one!

🤣😂🤣😂

Extremely helpful, yes.

Cute pic

Of mice and men......

Yeah, but if you were a billionaire, would you fund him substantially and graciously?

@@ogungou9 100%. I most definitely want to live a long healthy life plus I have a personal vendetta with diseases. Cancer killed my mom in her 40s. I know this is not directly about cancer but who knows where his researches will lead us. Preventions and Cures maybe.

Kirk Buchanan I’m with you; if back him 100% too if I had the money 💰

Pharma will lock the door to public success. If will be a very private success

Ogun Gou I'm still young so I'm gonna go get the money for funding

He looks younger than his age...

one of secrets to living to 100 is proper food, toxic one gets stores in our bodies for years and years and eventually coming up and some for of diseases, natural food (and not all) can help you live longer. Feel free to read some articles about that - but be aware there's lot of noise in it - false theories etc. try to verify elsewhere everything you read about it

@@orchidpearlwhite732 Botox and filler helps.

Well, if SENS and Aubrey de Grey are right, you'll not just be living old longer, you'll be reversing your age to become young again!

Just live a fulfilled life, if you are content with the life you have live it wouldn't matter if you die tomorrow, next month, or next year.

Are you taking 1g of reservatrol/day?

So what do you do?

@@ShroomGill join her class (pay $999) to find out!

What s the name of the pills you are taking ..?

@@almamunoz5276 None. It's all endogenous. I do take some vitamins but if I take them or not this happens because of natural things I do at home. Does that help?

@@ShroomGill I teach people true mastery over life, and I teach how to look and feel younger. I have 2 podcasts also and am an actress and a speaker, and have written 3 books. What do you do?

The health promises of boosting an important metabolic molecule may be clouded by its possible role in promoting cancer-cell growth. www.scientificamerican.com/article/cancer-research-points-to-key-unknowns-about-popular-antiaging-supplements/ SIRTs are involved in many important biological processes and play a critical role in cancer initiation, promotion, and progression. Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype. www.ncbi.nlm.nih.gov/pmc/articles/PMC6363704/ Dipartimento di Medicina di Precisione, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy (2019) "SIRT1 is involved in the initiation, promotion, and progression of several malignant tumors including prostate cancer (Jung-Hynes et al., 2009), breast cancer (Jin et al., 2018), lung cancer (Han et al., 2013), leukemia (Chen and Bhatia, 2013), colon cancer (Lin and Fang, 2013), melanoma (Ohanna et al., 2014), and ovarian and gastric cancer (Han et al., 2013; Shuang et al., 2015)."

So how is it going, three years later? Also, which NMN exactly do you consume?

Same here 🤸

Keep in mind that others are also working on this. The “partial cellular reprogramming” seems promising.

I really hope David achieves something great with his but imho what is really hopeful is the growing number of biotechnology companies investing in this field. If the science can continue showing it can be done there could be a huge acceleration of progress in the years to come.

I’ve been using a formula based on his research for a little over 2 years. So much has improved!!

Don't just be hopeful, Margics 🙂 because hope is not enough when action can be done: Donate in favor of the anti-aging research as much as you can, even just €1 per month like me (I'm still poor and I can't afford more). You can donate to the SENS Research Foundation here, for example: www.sens.org/get-involved/donate/

OPEN MIND Wow and he’s white??? Would never guessed 50! Black don’t crack

@@samsun01 ehhh what

yeah, but the speech sounds like an intro to a new zombie apocalypse

@@cryptoshi9636 And yet white people live on average 10 years longer than black people in the usa lol

the size of his ears says hes about 50, cant stop your ears from growing

that is because he had this speech memorized since 200 years ago

@@danielmanahan692 you have By

This is how it sounds when an expert speaks. Unfortunately in society today we hide our experts under mountains of Grant proposals while we let the clowns with no practical competency to speak of run the world. Occasional breakthroughs of transcendent, species-level imperatives like this one (plus the institution known as Elon Musk) are exceptions defining the rule.

@@josephkellum2083 Yes. It’s a shame anyone will need to be “amazed” by a highly trained academic. There are lots of them out there but we’re in an anti-intellectual culture where dumbing down is the rule and intellect is often mocked and derided to make the intellectually lazy feel better about themselves. Watch out as this could result in a moron becoming president.

It was very natural

We won't be immortal. But if we can be healthy and productive for longer maybe Social Security won't go bankrupt.

death is inevitable, fear of death is not, Humans are curious to want to everything except death and what beyond death.

@@MrManny075 If we were created by some kind of good force, then there should be a way for us to avoid all suffering to be fair. That would include watching yourself decay in the mirror by a process we call ageing.

@@NeoFrontierTechnologies no such thing if

Hope one of theme not beeing zombies

Check out his interviews from around 6-12 months ago, frown lines, nasty wrinkles that looked like a road map- Now, gone and he seemingly cannot move parts of his face...Stroke? No, BOTOX!

Rumor has it that he had Christian Slater lookalike surgery...

That only works on mice

Lol it takes a year for him to get to the point!

@@lyndenmanning8669 you are absolutely right. He looks like he's 50 or more. I just looked at his close up photos on google. He has so many wrinkles especially around his eyes.

I see what you're doing.... trying to outlive us, huh? 😂

Quick your hired,run to Atlanta wearing no clothes in the middle of winter, packing meals not necessary and do it at night when you wont be exposed to the Sun and no cheating by stopping at any convenience stores to use their microwave,and when you get here will have a nice cold shower waiting and a bowl of hot soup of onions ,cabbage and carrots

I wish more people had your attitude Kelly. It amazes me that there are so many initiatives out there for every stupid thing under the sun but only a tiny fraction is put into age research.

I think I know you, you said your a nurse!!! Don't you live in Oregon

We literally have nothing to lose trying to find elixir of youth, we may as well die trying. I myself am not really phased by dying. I dont wanna be old god damn it lol.

@anders damin acording to aubrey de grey calico is a waste of money

@anders damin of course, ive been looking at all of this for like 5 years now. Aubrey says that they're doing basic research on how metabolism works and how to slow it down, he thinks that its a dead end that will eventually lead nowhere, since (acording to him) we cant tweak metabolism, and we have to treat damage directly. However, i hope sinclair and steve hovard are right about their epigenetics theory as the source of all damage. That would be a huge leap foward.

Aubrey actually says that metabolism is far too complex to be helpful to us now. Eventually, yes, we will crack metabolism, but it could be a century from now or whatever.

The fact that Calico has been at this for six years with huge funding and has produced absolutely nothing or has publicized nothing tells me everything I need to know. I hope I'm wrong though.

@@squamish4244 maybe an AGI could decipher metabolism sooner than we think

. . . when somebody makes a living out of ageing . . .

His youth secret might be that he dedicated (donated) his life (some 50 years) to ageing and became a teenager. Worth a try!

He is simply a well trained scientist who sees the benefit of this endeavor. And there are many others like him.

Actually you do have to age even if u take those shot like what David said that can reverse age by decades. He use a word ‘reset’ so it’s like u age and you reverse it so diseases will be created while aging, we can not stop aging but scientists are trying to reset it.

I don’t know if you’ve been keeping up on the research, but over the last three years since you commented, David and people like him have made huge progress

⁠@@Crescent-IVI’m new to all of this but could you elaborate on the progress that’s been made?

Copyrights make money

"It's not as if the Universe doesn't have the space." Thanos would disagree with you. 😉

I completely agree with you. However, the physical appearance ("cosmetic") is a very important component for psychological well-being, needless to lie. And in any case the appearance reflects the functionality, as always happens in biology. "Aging Looks Are Not Just a Matter of Aesthetics": www.leafscience.org/aging-more-than-aesthetics/

it's hard to believe that googlers and whoever else is reading comments here would up vote such stupidity. For starters - if you will be able to 'upload' your personality / mind to the brain of another person (which will never happen, it's just a weird pipe dream of fiction literature) - this action means that you have to 'wipe out' the mind of that 20 yrs old clone which is in other words equivalent to a CRIME OF MURDER. Think for a second- how that person (clone) would feel if he/she learns that their only purpose in life is being body double for some schmuck, who will wipe their mind / memory /soul, if you like- just to replace it with theirs, lol.. beyond ridiculous..

I did the NAD+ IV drip at age 39-40 about ten months ago and it was very powerful. My mental acuity increased, soreness in my muscles and joints decreased, inflammation decreased and I gained strength, flexibility and mild gains in agility. The process literally 'purified' my body (you can imagine what the purification was like ;) So yes, I am 40 when I look in the mirror but I don't feel it. I go every three months now. You can take the pills too, or the powder, both are sold on Amazon or you can order them from a naturopath who does NAD drips...they aren't as effective as the drips but they ARE effective. Ideally, you should purchase tablets that you can dissolve under the tongue, as that maximizes absorption into the bloodstream. I also do hot yoga and hit the gym. I'm probably as fit and strong as I've ever been. So 42 is nothing to fear these days, although it does take some serious contemplation and maybe a mid-life crisis to realize that. Another thing that is often neglected is the mind. We have piled on 20 years of adult shit, caution, bitterness, anxiety, neuroses etc. that we lacked when our minds were young. In a phrase, life has kicked our asses. Therefore, it is important to explore potential brain technologies to basically function as meditation on steroids, such as neurofeedback (I use NeurOptimal) to calm the chattering mind and remove layers of trauma. This device has the potential to make us feel psychologically younger when we were bulletproof while retaining the wisdom of experience. Many other devices are coming out or are already out. Ask me if you want to know more :)

What about the clone? It's a separate human, unless we found a way to harvest bodies without brains. Also there a dis

👍👍👍🏽

Buy a thousand copies of his book and give them to your well educated friends. This will trigger an avalanche of inquiry that will result in increased funding of Dr. Sinclair's very expensive research.😇

CBD will help glaucoma.

Yes david is the most valuable person

ask your doctor for better glasses, he is old the face is not everything what decide about age

@@softrek His clothes are 20 like my socks are 20 like I'm 30 years older than my college physics student. No, make that 35 older...

@@drbonesshow1 are you a jew?

Softreck Softreck Mueller is not even close to being a Jewish name

@@ytyt3922 they are changing names like you pants

You can use ‘Tru Niagen’ it works! You will sleep better but also look younger, I’m way younger than 50 but I noticed that my skin looks way younger since I’m using this product.

I don't give a damn what they discover, but I guarantee you WILL NOT live to 1000 year, you won't even live to 200 years.

I agree!! Check out Dr. Aubrey De Grey also. And Calico.

You could always ask to come back.

I am happy to find someone else who wants to live 1000 years! So many negative people hate this world, hate life, have given up on humanity, and look forward to some fantasized after life. I love this life and want to explore it, change the world for the better, and be alive for centuries!

@Ray J. marxism

Just drop the fucking meat

What NMN are you taking? Looking at amazon but not sure about them.

Hello! It feels that you are describing me! 😊After reading the book Paul C. Bragg "The miracle of fasting", I was 19 at that time, but I was so impressed that I have made a decision to give it a try and to see how it actually works in reality. I started with 3 days fasting (that was a mistake, because I never done that in my life...) , I thought that I will faint a couple times, but I survived and then I tryed slowly to come back to the regular eating, it was really hard not to overeat. It's really a challenge. Right now I am 48 and I have decided to do a regular 36 hours fasting once a week and I feel great! I have so much energy and I don't feel hungry at all. Going for 3 days fasting the next week, will see how is going to work. The hardest part is the cold when your metabolism is slowing down. I am trying to be more active then, to walk more, I wish that I could work out, but it's not good while you are fasting. I can't do only with the water for the same reason, so I take a tea, green tea is good especially if you have headaches while fasting, but water is essential. I drink min 2 liters per day anyways, so while fasting is even more. Yes, cutting sugar is the hardest part, I don't use any white sugar while ago, but a honey or maple syrup is still on my list, otherwise I have no energy, my blood pressure becomes much lower while fasting, otherwise it's perfect. I don't use any coffee for 3 years now, it was hard, because it's usual to drink so much coffee at work here is Sweden and it's very strong coffee. It took around six month until I could walk away from a coffee shop without just enjoying the smell like an ex smoker who enjoys another person smoking beside. Now coffee beans smells horrible to me, like something burned and unpleasant. Cheese was another challenge of mine, before I got lactose intolerant 4 years ago I use to eat it every single day, maybe that's why... 🤔 I don't see another reason, once my body just said: okay, honey, enough is enough, your cheese intake in this life is just finished... 🙄😏 Otherwise I am quite good with my diet, trying to eat as much organic fruits and vegetables as I can. Beans and lentils are good meat replacement. I still need some fish (mostly wild salmon or herring ) as a protein and vit D provider, but meat intake I have limited very much lately, I still enjoy some turkey breast sometimes, but like only once a week or less often. I hope I am on a good path. I workout regularly for 10 years now, I love to move all the time. I think that I will be fine, I got good genes as well, my mom is 73, she still don't need glasses just while she is writing something, almost no grey hair whatsoever, amazing memory (I wish I would have that!) she is growing her own natural food in the village, moving a lot, excercising every day. My dad died a few years ago, but he also had a terrible diet, nobody could change his habits, not even my mom, may rest he in piece. 😟 I am trying my best here, I never smoked, never used any alcohol in my life, the last and most difficult one is to cut completely a drug called SUGAR. The longest time I survived without any sugar whatsoever was for 6 weeks... 😏 It was a hell, just because my daughter likes to bake sweets. 🍰🍮🍪 I felt much better though, it's nothing to compare, it really takes a lot of power of will, as an addiction is 10 times stronger than to cocain... 😒 If I can do it, so do you! Good luck and stay healthy people! 🍀

that s amazing I am happy for you . I hope I can succeed too

Is cheese that bad for you? Cut yourself some slack and enjoy some cheese.

Mathieu G how'd you get hold of it? Couldn't find it anywhere

@@unknownchannel3141 Amazon has it, reading the digital version

Soham Sadhukhan I purchased mine at Costco and I’m enjoying it.

For Sinclair's twin mouse, the first who came to my mind is Christopher Nolan, who is also roughly the same calendar age ...while looking more than a decade older.

Why was I saying the same thing

Hahahaha totally!

Thank you! Couldn't think of who he looked like haha 🤣

@@dahawk8574 Looks nothing like Noland.

Fasting is a crucial part of life. I'm not talking about lent, or Persian fast for part of the year, but fasting for 1 whole day, 2 days, and 3 days, on a very regular basis. And no sugar, sugar is lethal.

But is that going to result in a more meaningful life for the average person ? Even if people had all the time in the world, they will never be able to do all the things they wanted to do, and even if they do it again and again is that going to result in a similar experience to the first time ? I don't think so. At some point the law of diminishing returns is going to kick in and you are going to end up with people looking to suicide to relieve themselves of unending boredom.

Loo Eli good thing for the gene poole

@anders damin true, good point.

With the realization that death is a rarity and that you and the tree will likely always be there, I can imagine it is going to be hell on earth for a lot of people.

no not really, u will get to a point you will say I have had enough thank you, even for a tomorrow and its true

Botox?

@@tf2368 He explains what he takes on the joe rogan podcast.

Suggestion is he does botox

Botox isn't everything. You still ha e to eat right and sleep properly excersize etc

Sinclair doesn’t think the jury is out on resveratrol. He takes 1 gm per day. I think the known research and safety profile are almost astounding. If I could take only 1 it would be resveratrol. But I take more than 1.

Be careful about losing too much weight. It's actually better going into 'old age' with a few extra pounds for much needed energy when your appetite begins to falter....and you eat less and less and less. 😇

Where’s the supplements to buy

What NMN supplements do you take?

Couldn't agree more

Are there any side effects of nmn?

For how long have you being taking it?

Which brand?

I could certainly use more energy.

Hi what supplements do you take?

@@irumkhan3381 The list is extensive. You may have to narrow your question up a little, such as "what supplements do (I) take for longevity, or focus, or daily regiment."

The real problem with all of this research into the biochemistry of aging is that we are living in a world grossly contaminated with thousands of chemicals known to be harmful to human beings. With the dumping of human trash in the oceans and burying it in the ground, this toxic chemical contamination problem will only increase exponentially as the world population increases. Ask yourself this question: What happened to all the nuclear fallout that resulted from above ground nuclear testing on this planet from 1945 to 1963??😇

@lanamuir9352 how And why the fuck would you enjoy the aging process why would that be something you would openly express positive comments about aging Evetually having little to no mobility and looking like a wrinkled prune and hair falling out