Years after striking a deal with the demon Mephisto. Johnny Blaze have isolated himself from those who are close to him, including Roxanne Simpson. Roxanne have saved Johnny from being taken away to Mephisto's Realm with her pure heart against the demon himself. Unknown to Johnny, however, is that Mephisto have merged him with Zarathos, the Spirit of Vengeance!
Johnny Blaze realizes that he will turn into the Ghost Rider whenever the sun goes down. The spirit within him craves for those who spills innocent blood and thus striking fear into every mortals' hearts.
He was guilt ridden over the death of his stepfather, Crash Simpson, whom Mephisto allow to die after curing his cancer. Johnny Blaze will try to find a way to seek vengeance on Mephisto for ruining his life and regain his humanity once again.