The Discovery of Insulin - The Miracle - Medical History - Extra History - Part 1

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Extra History

Extra History

2 роки тому

If you live in Minnesota, learn more at U21checkups.com. If you don’t, check here: www.medicaid.gov/medicaid/ben...
Jan 19th 1922, University of Toronto. Day and night for 11 days James Collip has been in the lab preparing sample after sample of a hormone taken from beef pancreas. His team hopes this will save thousands of children a year but in truth, it's one specific child Collip is trying to save, and it's a race for the cure.
Follow John James Rikard Macleod, Frederick Banting, Charles Best, and James Collip in the discovery of insulin, a miracle cure.
Part One - The Miracle: • The Discovery of Insul...
Part Two- Free for All: • The Discovery of Insul...
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by: Tiffany Roman
#ExtraHistory #Insulin #MedicalHistory

КОМЕНТАРІ: 742
@extrahistory
@extrahistory 2 роки тому
If you live in Minnesota, learn more at U21checkups.com. If you don’t, check here: www.medicaid.gov/medicaid/benefits/epsdt/index.html
@thepoglin8479
@thepoglin8479 2 роки тому
wait how is this post 2 days old?
@professorcube5104
@professorcube5104 2 роки тому
@@thepoglin8479 it was privated
@Ceo_of_Noobs
@Ceo_of_Noobs 2 роки тому
WASNT NICOLAE PAULESCU WHO DISCOVERD THE INSULIN
@brentgibson8198
@brentgibson8198 2 роки тому
Wait you still didn’t finish the takeover of India series
@berkeleysmith6630
@berkeleysmith6630 2 роки тому
A STORY ABOUT A CANADIAN LETS GOOO
@SpoopySquid
@SpoopySquid 2 роки тому
"They resolved not to profit off this discovery" US pharmaceutical companies: I'll pretend I didn't hear that
@GiordanDiodato
@GiordanDiodato 2 роки тому
@@scottanno8861 ok antisemite
@GiordanDiodato
@GiordanDiodato 2 роки тому
if anything, I blame insurance not covering enough
@sbatou87
@sbatou87 2 роки тому
It's not just insulin, but other drugs, too.
@wallywallendo
@wallywallendo 2 роки тому
@@GiordanDiodato nope it’s pharma, and government refusal to advance along with the rest of the developed world with free healthcare.
@dallindespain4093
@dallindespain4093 2 роки тому
Right now one vile of insulin costs about $100
@jeffmcarthur5617
@jeffmcarthur5617 2 роки тому
"The child is dying!" "Quick! Get him coffee and booze!"
@N00b0super
@N00b0super 2 роки тому
Alcohol doesn't necessarily lower blood sugar, it's different for every person. I'm diabetic and my blood sugar may either get really high or really low whenever I get wasted even if I am carefully controlling it. And coffee is probably one of the worst things to give to someone with hyperglicemia: your heart may simply not withstand pumping thicker blood real fast (my heartrate when I have high blood sugar gets high even without coffee).
@hughGrant748
@hughGrant748 2 роки тому
Booze
@laureneras9523
@laureneras9523 2 роки тому
I mean what I want on my death bed. Lol
@Docwilson91
@Docwilson91 2 роки тому
@@user-pj5wf3jm2u I would have thought the opposite for alcohol, since alcohol breaks down in to sugar.
@andrewenderfrost8161
@andrewenderfrost8161 2 роки тому
@@Docwilson91 alcohol makes your blood sugar raise first, and then drop dangerously.
@ShortHax
@ShortHax 2 роки тому
The discovery was wonderful for the kids but imagine how the parents must have felt? Probably one of the greatest days of their lives. Imagine the dread they must have felt knowing their kid had what was basically a death sentence
@Sqk.
@Sqk. 2 роки тому
Exactly.
@ProvidenceNL
@ProvidenceNL 2 роки тому
I kinda choked up a bit at that part honestly.
@NewWaveEnthusiast
@NewWaveEnthusiast 2 роки тому
Hello. Again.
@thundervaart
@thundervaart 2 роки тому
2 years ago, at 24 years old, being 1.80 m tall weighing ca. 75 kg, I was diagnosed with Diabetes. Docs said basically since I'm not fat or old it's most likely type 1 Diabetes. About 1 week before the diagnosis, I weighed ca. 80 kg. In just one week I dropped 5 kg all the while eating like crazy, especially sugar (which was weird for me, since I wasn't that much of a sweets snacker), getting up every night to drink about 2 litres of water and piss about 6 times. Only at night, imagine the days. Also, I normally sleep through the night "in one sitting". I felt incredibly weak and weirdly hungry, my eyesight was extremely blurry and I was constantly in a daze. Sure, those parents probably had the greatest day of their lives, but those kids must have been through hell and beyond. Finally feeling energized, not having the urge to stuff yourself or drink water like you went through a desert for 3 days straight. Having hope not to die with your 10 years of age. I only felt symptoms for a couple of weeks, they suffered months or even years AND most likely felt responsible for their parents sadness. It's kind of macabre to say, but.. you "may always" have another kid, but these kids would never have another life (I know it's far more complex, hence quotation marks). I know what you wanna say and I'm not challenging you think otherwise, but getting handed back a chance at life as a "healthy human" is far more than just wonderful. Or at least, what I wanna say is, of course one shouldn't forget the parents, but I think those kids were the happiest on the days of their first injections. Then again, you might be a parent, I'm a guy with Diabetes, so no wonder I feel the kids should be the focus and not the parents. In the end, there's nothing wrong with your comment, this text is only a justification as to why I feel in disagreement with it. Guess it's too personal for me lol I'm just grateful I may live on, I can't imagine how utterly thankful those kids must have been. Have a nice day everyone!
@IcecreamMcGuy
@IcecreamMcGuy 2 роки тому
Yeah
@19MAD95
@19MAD95 2 роки тому
Nothing like a good fist fight to dissuade greed.
@notme8232
@notme8232 2 роки тому
Someone needs to tell Banting about the drug market today, he'd probably physically manifest as the Doom Slayer
@robert-janthuis9927
@robert-janthuis9927 2 роки тому
@@notme8232 Nah, we'd suddenly get treated to a real life vigilante, only known as Bantman.
@jordisaura6748
@jordisaura6748 2 роки тому
often I feel tempted
@ecurewitz
@ecurewitz 2 роки тому
these days greed is maximized
@fuzzyhair321
@fuzzyhair321 2 роки тому
sir you have an option tell me or lets say broken bones will be made and you've got a lot of bones
@Eramiserasmus
@Eramiserasmus 2 роки тому
This is always inspiring to think about. They closed in on something and have saved thousands of thousands of lives. Shame about it's price in the modern pharmacy.
@osonhouston
@osonhouston 2 роки тому
Millions of lives and counting, myself included.
@DomyTheMad420
@DomyTheMad420 2 роки тому
aaaaaaaaaaaaaaaaaaaaaaaaaaaahahahahahahaha you AMERICANS crack me up.
@killme9909
@killme9909 2 роки тому
@@DomyTheMad420 hahahahaha, yeah we totaaaaally dont want free healthcare and the ability to get help without being in debt the rest of our live but neither goverment party will give us that. Yeah we want to be in debt, its our fault
@professorcube5104
@professorcube5104 2 роки тому
@@DomyTheMad420 indeed, laugh at our suffering
@LillyP-xs5qe
@LillyP-xs5qe 2 роки тому
Empathy and care made it possible. Capitalism made it inaccessible.
@hardhatlunchpal
@hardhatlunchpal 2 роки тому
There is something very heartwarming about hearing that they rushed to the diabetic ward and injected the children with insulin that clearly saved their lives. It reminds me of a CBS Sunday Morning episode that's just all of a sudden tearing at your heart.
@Lazarus1095
@Lazarus1095 2 роки тому
I admire Banting's response to the standard practices of the modern pharmaceutical industry. We could use a few more guys like him.
@IcecreamMcGuy
@IcecreamMcGuy 2 роки тому
@@Lazarus1095 it wasn’t only Banting though he had a humongous part in it
@MerkhVision
@MerkhVision 2 роки тому
@@IcecreamMcGuy I think they’re talking about his anti-greed stance, not his overall contributions to the project.
@ShankarSivarajan
@ShankarSivarajan 2 роки тому
If you this that's admirable (as you should), then you'd be the most despicable sort of hypocrite if you support the FDA preventing people from getting access to medicine they want.
@Lazarus1095
@Lazarus1095 2 роки тому
@@ShankarSivarajan Um, no, that doesn't follow. The FDA prevents drugs that don't work or that have catastrophic side effects from going onto the market. Thalidomide is the classic example. Did you mean the Patent Office?
@smoche
@smoche 2 роки тому
I can only imagine how Banting would feel seeing countless pharmaceutical companies benefit from something he felt was so essential to save human lives that he wouldn't patent it
@Demopans5990
@Demopans5990 2 роки тому
Open source wasn't a thing back then. Think one of the first thing I would do is to hand him a Apache 3.0 license and a lawyer
@SuperNova-so2cj
@SuperNova-so2cj 2 роки тому
maybe we should take notes as to how he convinced collip not to profit off it
@memesthatmakeyouwannadie3133
@memesthatmakeyouwannadie3133 Рік тому
Go ham on them like he went on Collip. Probably be proud of Canada for not succumbing to greed and ensuring everyone who needs it can get it for free/cheap.
@laurakastrup
@laurakastrup Рік тому
My man would have gone to big pharma personally and beat someone’s ass.
@nicholasarmstrong643
@nicholasarmstrong643 Місяць тому
Type 1, I don't know if I feel anything is simultaneously as evil and prevalent as charging people money for life sustaining medicine.
@basoon87
@basoon87 2 роки тому
Good for Banting. I'd have knocked out that guy too for suggesting he would patent the purification process. For something that was discovered almost a hundred years ago and was not patented, insulin sure is way too expensive today in my home country (0 points for guessing where). Imagine how bad it could be if it had been patented from the start.
@millersam07
@millersam07 2 роки тому
I think we need Banting to come back and beat up the for profit medical system we currently have
@Echo81Rumple83
@Echo81Rumple83 2 роки тому
@@millersam07 amen
@jannegrey593
@jannegrey593 2 роки тому
Insulin is also expensive in other places. In Poland my father's stock of insulin for 8 months costs around 200 dollars. Thankfully Glucometers are free with prescription for strips (I sent one to a friend in US) and strips with prescription cost only about a dollar for 50 (without prescription price is about 10 times). The reason partially is that companies use their own refined methods of mass producing insulin. By that I mean artificial insulin. Of course it should be cheaper, but that is only part of problems your country is facing. Without Universal Healthcare system - every insurance company negotiates for themselves. In Poland government speaks for 38 million people, so they can bring the prices down.
@abooper960
@abooper960 2 роки тому
It’s expensive because Canada sold the patent for it to the USA
@matthewferrantino9521
@matthewferrantino9521 2 роки тому
Private profiting is a two edged sword. In the hands of someone less trustworthy it would make it worse. But someone who asserted themselves as wanting to control it only because they distrusted other organizations but trying genuinely to make it cheaper for people can probably do more for people than the government. It's like the risk of a bad king vs wanting a good king to be powerful making it hard to figure out if monarchy is a better system or not. In the end really neither system is better: individual people will either use the systems in good faith, or they won't. A good person can make do with any system.
@lopali
@lopali 2 роки тому
Nicolae Paulescu also made significant contributions to the discovery of insulin. He made a similar extract, and by the time Banting and Best isolated insulin in February 1922, he was already awaiting the patent confirmation for his 'pancreine'. Roif Luft, president of the International Diabetes Federation in 1971 and chairman of the Nobel Prize Committee for Physiology and Medicine, stated that "One fact remains, namely that the earlier discovery made by Paulescu was misinterpreted by Banting and Best for reasons which we cannot know anything about today … In my opinion, the [Nobel] prize should-without any doubt-have been shared between Paulescu, Banting and Best." Please at least make a note in the 'Lies' episode
@su1t0n11
@su1t0n11 2 роки тому
Thank you! It's pretty sad that he dosen't really get recognition if at all.
@donaldduck9884
@donaldduck9884 2 роки тому
I'm curious if Paulescu the ultra nationalistic antisemitism who administrated the insulin extract rectally instead, had same opinion about the medicine most be cheap and access for everyone have right and afford to buy it?
@matthewferrantino9521
@matthewferrantino9521 2 роки тому
My take might be kind of hot here, but it sounds like Banting wouldn't have liked anyone who wanted to patent, and maybe he let that straight up prejudice him?
@mattmathematics3591
@mattmathematics3591 Рік тому
@@donaldduck9884what does any of that have to do with this 🤷 ford was an absolute ahole u still learn abt him and the founding fathers owned slaves
@donaldduck9884
@donaldduck9884 Рік тому
@@mattmathematics3591 Founding father? I'm totally confused what you are talking about so pls explain better what you talking about?
@matthewsteigauf470
@matthewsteigauf470 2 роки тому
I'd love to see a series like this or a one off on the development of the pacemaker. I got my degree in biomedical engineering from the University of Minnesota and it's kinda just a common legend there. And, WOW, is it a good example of why having regulations are good.
@malachiphoniex8501
@malachiphoniex8501 2 роки тому
I second this.
@militustoica
@militustoica 2 роки тому
My 86 year old grandmother whom I am very close to had to get one. She got CoVid-19 and had no primary symptoms whatsoever. Then almost as soon as she recovered she developed major arrhythmias. She had a profoundly healthy heart for her age before then and no cardiac family history. The doctors said it was most likely the far more pernicious Post-Acute Sequillae. They were able to put it in with pin-hole laprascopy in twilight sedation, but she goes in about once every 30-60 days because of remote monitoring issues now for medication adjustments or defribullation.
@danknigel5430
@danknigel5430 2 роки тому
Jarvik artificial heart would be cool too
@JackDelta
@JackDelta 2 роки тому
Yeah that would be cool
@mckayleepugmire9947
@mckayleepugmire9947 2 роки тому
The end of this comment makes me worry about the test subject involved in the project, but my grandma's had a pacemaker for years sooo...
@Gwallacec2
@Gwallacec2 2 роки тому
Matt, James, Rob, Dan.... Thank you for posting this. Thank you for making this series. I had no idea the toll diabities takes on a person both Type 1 and Type 2 until I heard the story from my girlfriend. She has had T1D since she was five and ever since I found out about her condition I've been looking for videos that advocate for information to be shared that's factual like I know your channel strives for. The price of any disease is so high and showing the emotional toll is so critical. I cant wait for the rest of these videos to come out. I've supported you for years and you continue to surpize me constantly with the critical information you share with the UKposts community. I also am so happy to see the Medicaid link and the advocacy. Together through information we can cure the world. I would be interested to see more coverage of rare diseases on this channel. Thanks again!
@briannamcdaniel266
@briannamcdaniel266 Рік тому
Is she doing better now?
@John-Ginger
@John-Ginger 2 роки тому
Imagine the euphoria in the room with the six comatose kids, with the first starting to wake up within a short period of time. The knowledge that it worked and wasn't a fluke and that it will change the world.
@ModelAAA90
@ModelAAA90 2 роки тому
Fame, Recognition, and Fortune. Some of many reasons why humanity may never know progress among its good and talented men and women… 😔
@bungalo50
@bungalo50 2 роки тому
Wealth, fame, power. The world had it all won by one man: the Pirate King, Gold Roger!
@Rafaelrgm
@Rafaelrgm 2 роки тому
Funny is that MOSTE of them generally agreed to forfeit the fortune part, from what was said in the video, the fights seemed to be mostly boiled down to fame and recognition.
@matthewferrantino9521
@matthewferrantino9521 2 роки тому
I think that when people are desperate, they honestly will let go of these temptations. Everyone is naturally tempted, but most want to overcome it.
@whathell6t
@whathell6t 2 роки тому
@@bungalo50 *Pirate King, Atomsk; not Gold Roger.
@Kopeleto
@Kopeleto 2 роки тому
@@bungalo50 Actually, it's Gol D. Roger.
@crashedfighterproductions
@crashedfighterproductions 2 роки тому
I owe these men my life. I was diagnosed at 8 months old, and nearly died. 20 years later, and I'm still here. I'm super excited for this series!
@Syurtpiutha
@Syurtpiutha 2 роки тому
"They resolved not to profit of this discovery". A noble goal. Too bad that others did not share this conviction. In case the price-hiking of insulin over the past decade wasn't enraging enough on its own.
@thinkfact
@thinkfact 2 роки тому
Anybody with the loved one who's suffering from the effects of diabetes, this sort of stuff can actually make you emotional.
@MontyBeda
@MontyBeda 2 роки тому
My son was diagnosed with diabetes two weeks ago so he is alive only thanks to insulin now. So really looking forward to watching this after he will be sleeping in half an hour hopefully :-)
@kaymuldoon3575
@kaymuldoon3575 2 роки тому
Sending good thoughts for your son. 🙏🏻🙏🏻🙏🏻
@Kaanfight
@Kaanfight 2 роки тому
The discovery of Recombinant Insulin also was huge in making life better for people with diabetes. As stated in the video, the 14 year old had an allergic reaction to the beef insulin. Recombinant Insulin was created by using bacteria to create human insulin by biomedical engineering in the 70s. This greatly reduced the risk of an allergic reaction due to impurities and the foreign elements in boar and cadaver insulin, which were used since its first discovery. Science!
@kestrels-in-the-sky
@kestrels-in-the-sky 2 роки тому
How much is his insulin costing you If your in the us
@MontyBeda
@MontyBeda 2 роки тому
@@kestrels-in-the-sky Luckily we are in Czech republic so we are not paying anything. Got insulin pump for free, sensors for free, insulin for free, education about it all, glucose meter which also measures ketone levels and all the testing strips for it (just both one set of ketone strips with my own money), all the infusion sets for the insuline pump and also disinfectant and such for the changing of them. And also the emergency syringe for hypoglycemic shock was for free. So glad we live in developed country with universal healthcare as quick sum of all the stuff is around 130 000 CZK so around 6 000 USD.
@tntfreddan3138
@tntfreddan3138 2 роки тому
I'm gonna ruin you moment of 69 likes. Here's a like to you and your son. Give him a hug from me. I may not have diabetes but I at least know that emotional support is very important in trying times. I've had a lot of trying times but rarely got the support I needed. I wish him well. 😁
@peregrinemiles7936
@peregrinemiles7936 2 роки тому
Humans: simultaneously the most amazing and most horrifying thing. As sir Terry Pratchett put it; “ where the falling angel meets the rising ape”
@SebastTapia
@SebastTapia 2 роки тому
*Terry Pratchett voted best author ever*
@adunsavior
@adunsavior 2 роки тому
We need Banting to come back as a ghost and haunt the pharmaceutical executives and shareholders day in and day out.
@_ayohee
@_ayohee 11 місяців тому
Ghost of medicine past
@penname8441
@penname8441 10 місяців тому
+
@elliotttheneko
@elliotttheneko 2 роки тому
When thinking about island riches, we think of spices, sugar, exotic fruits and the like. But perhaps, the most important of all island riches are the ones in us all. (Islets of Langerhans)
@Praisethesunson
@Praisethesunson 2 роки тому
Let's plunder those islands for corporate profit.
@espio87
@espio87 2 роки тому
I claim those islets in the name of the Spanish Crown and our Beloved King Ferdinand II of Aragon and our Queen Isabella I of Castile! **plants flag into my own pancreas**
@andrewenderfrost8161
@andrewenderfrost8161 2 роки тому
@@espio87 you can have mine :/ they're not functional anyway
@IcecreamMcGuy
@IcecreamMcGuy 2 роки тому
Well time to colonize my body britain and France eat your HEART out
@theoutlook55
@theoutlook55 2 роки тому
Nice man.
@stuartwhite4610
@stuartwhite4610 2 роки тому
Always makes me feel pride as a Canadian that someone from my country developed this treatment. And was selfless about distributing
@zakariaraqiq
@zakariaraqiq 11 місяців тому
From a type 1 diabetic, thank u Canada
@stefanbirlog4622
@stefanbirlog4622 11 місяців тому
​@@zakariaraqiq Romania did it first
@jamesboyle6134
@jamesboyle6134 2 роки тому
This one really hits me where I live. I am Type 1 diabetic, and only discovered when I was brought to Accident & Emergency (what we call ER). I had been feeling rundown with a terrible thirst for a few weeks. Then the vomiting and cramps started. And then the vomit turned black... When the nurses examined me, it turned out I was suffering from diabetic ketoacidosis, which happens when a person's blood sugar is far too high for far too long. Needless to say, I was in the High Dependency Unit and then a general diabetes ward for about a week. Without insulin, I literally would not be alive today.
@royaltytries
@royaltytries 2 роки тому
When I was a toddler , I was rushed to the hospital and later diagnosed with type 1 diabetes. Every day since, I use insulin to keep myself alive. And I’m so incredibly grateful, you guys are telling this story! 100 years ago, I would have been Pronounced dead as soon as I got diagnosed. Now? I can live my life, I just need a small injection once in a while and a machine that has insulin inside it to act as my pancreas. your telling the story to the people who have never heard it, who need to hear it! And to that? I am so incredibly grateful. Love you guys, You keep up the amazing videos and your great ♥️
@powersell8589
@powersell8589 2 роки тому
I am disappointed to see that there is no mention of Nicolae Paulescu or any other scientist before them.
@Itagamo
@Itagamo 2 роки тому
Yeah extra history.
@ZechsMerquise195
@ZechsMerquise195 2 роки тому
It's strange. My father had type 1 diabetes his entire life and I have a strong genetic disposition to developing diabetes. But I never thought to look up the history of Insulin. Thanks Extra Credits for once again broadening our minds and teaching us new stories.
@ttvnulatics3870
@ttvnulatics3870 2 роки тому
I have had diabetes for almost 7 years now, very glad medicine has progressed enough to keep me alive 👍🏻
@thecanadian8206
@thecanadian8206 2 роки тому
thx for your username and god bless you
@AegixDrakan
@AegixDrakan 2 роки тому
Best of luck managing your condition!
@andrewweitzman4006
@andrewweitzman4006 2 роки тому
What I enjoyed was both the heartwarming medical miracle story mixed with the acknowledgement of the deeply flawed people involved in it. *lays a wreath for the doggos*
@goranvujovic27
@goranvujovic27 2 роки тому
As a diabetic, this brings me great joy that you are dedicating a mini series to this. The history is very interesting and your guys videos are ones that I have been watching for years. So thank you.
@ArthurBCamara
@ArthurBCamara 2 роки тому
As a Type 1 diabetes myself, I'm literally with teary eyes to see something so meaningful for me in one of my favorite channels. Thank you. Thank you. Thank you.
@Sir_Uncle_Ned
@Sir_Uncle_Ned 2 роки тому
As a Type 1 Diabetic, I am very thankful that this discovery was made with an express desire against profit. I have lived with this condition for the better part of a decade now and in this age of modern medicine, it's just an inconvenience rather than a death sentence. I look forward to seeing more of this series.
@ChiaraVet
@ChiaraVet 2 роки тому
I deeply appreciate that you haven´t hidden the fact that this life changing achievement of modern science and medicine was made thanks to animal research (without the repeated experiments it would have took way longer to save those children and many others after them... and we have seen that time is never on the side of science). Even today that is a fundamental part of basic research, and the laws about animal welfare in place and the advanced technology allow us to avoid such cruel experiments. Many newspapers avoid reporting the part of a research that was done on animals and this is a type of misinformation we need to avoid. I understand that it is a difficult topic but we also need to say things how they are, we need to face reality.
@hopeless6905
@hopeless6905 2 роки тому
I love that you’re doing this. My girlfriend is a type 1 diabetic and it’s awesome to learn the history of what keeps her alive
@bigj1905
@bigj1905 2 роки тому
You should create a “Extra Medicine” channel. I really like learning about the discovery of vaccines, the history of diseases, and other general medical knowledge.
@georgechapman9688
@georgechapman9688 2 роки тому
I'd watch that
@Overhazard
@Overhazard 2 роки тому
I'd like to see it expanded into an "Extra Science" channel. Interesting things occur in the other branches of science too, and its history thereof. Stuff like the life of Antoine Lavoisier (discovered oxygen, invented medical cross-ventilation, revolutionized tobacco farming, Mrs. Lavoisier translating scientific papers from English to French for him and his papers from French into English for publication, rewarded by being sent to the guillotine during the French Revolution), Erastothenes's technique in ancient Greece for measuring the circumference of the Earth to an error of less than 3% (they knew the world was spherical, and Aristotle could prove it in five different ways), the Stanford Prison Experiment (which had to be called off after less than halfway through due to the madness the people undergoing it were experiencing), and, while this is still ongoing, a rundown of the atomic elements discovered by Yuri Oganessian (who discovered or helped discover twelve elements--bohrium, meitnerium, hassium, darmstadtium, roentgenium, copernicium, nihonium, flerovium, moscovium, livermorium, tennessine, and oganesson, the last of which was named in his honor by his team--the most of any one person, and is still alive and still looking for more). Speaking of chemical elements, polonium has quite the rich history, used for both good and evil. Marie Curie named it to bring awareness of her home country of Poland, and it is extremely radioactive, so much that it was used by Russian spies to discreetly poison KGB defector Alexander Litvinenko...and was radioactive enough that the taxi he rode had to be decommissioned for being too radioactive to use simply because he sat in it for half an hour after ingesting a grain of polonium.
@history-jovian
@history-jovian 9 місяців тому
We already have too many extras. Extra SCIFI, Extra Credits and Extra history.
@battledroid7628
@battledroid7628 Місяць тому
@@history-jovianextra mythology
@andromeda331
@andromeda331 2 роки тому
Wow, how amazing. I can't imagine what it felt like to be a diabetic who thought you had a death sentence to find out that there was something that could save your life. Save countless lives. That's wonderful.
@feldmarschallvonbraunschwe4463
@feldmarschallvonbraunschwe4463 2 роки тому
Ah! My university, really cool to see some Canadian history. We don't get much coverage and this is a perfect topic!
@papplebeast5039
@papplebeast5039 2 роки тому
Type-1 and Type-2 diabetes aren't different because of the age of the person they inflict. Type-1 diabetes is when your body loses the ability to produce insulin. Type 2 diabetes is when your body becomes resistant to insulin. Type-2 diabetics still produce insulin.
@ZeMalta
@ZeMalta 2 роки тому
Man, I know life is hard, but damn, to hear them be so adamant in take no profit from this is very heartwarming.
@danielgraumann87
@danielgraumann87 2 роки тому
Being a type 1 diabetic, there discovery really saved my life and allowed me to grow to an age to have children and make memories with my family. However, there is still cost to it that is causing me great harm. From the high cost of the drug that keeps me alive day to day that has driven me into thousand of dollars in debt to the constant testing of my blood to keep track of my blood sugar levels and the hardness of trying to find nutrition information that I need to take the right amount of insulin. With these things still prevalent, it feels like there is no cure yet to the type 1 diabetes at least not until an artificial pancreas is made which I hope is soon. 🙏🙏
@rosiehawtrey
@rosiehawtrey 2 роки тому
You can buy handheld testers for a few tens of $. You need the test strips and those little snap pin things (don't know the technical term) but those will give you enough information about where your blood sugar is. Places like aliexpress or ebay or even Amazon if you want to buy Bezos more yachts. I'm guessing you are in the US - and Dr's will connive with the companies to reel you in for unnecessary lab tests that can be done on this sort of unit at home. Ex partner had it amongst other people. Test in the morning first thing and at night - if yours tends to go on the low side keep chocolate or something similar available at all times.
@kiranederlof5014
@kiranederlof5014 2 роки тому
My brother is diabetic, this is a series i look forward to watching.
@professorcube5104
@professorcube5104 2 роки тому
My grandfather is also diabetic
@royalewithcheese7
@royalewithcheese7 2 роки тому
American pharmaceutical companies: "We can milk this!"
@NoGoodHandlesLeft
@NoGoodHandlesLeft 2 роки тому
Fun Fact: Sir Frederick Banting did get his due and was one of the last Canadians given a knighthood.
@sethhomer1681
@sethhomer1681 2 роки тому
I myself have type 1 diabetes, so glad that we have insulin today, but I really wish that insulin was affordable here in the US
@MustardLadySaveMe
@MustardLadySaveMe 2 роки тому
How upsetting to learn that insulin was developed with the intention of being free to anyone who needs it. Pharmaceutical companies charge 25x the cost to produce insulin, and our government just sits back and says nothing while taking "donations" from those same companies.
@willtanker7684
@willtanker7684 2 роки тому
brilliant, a series on exactly how my life was saved! not living under the deadly healthcare system of the U.S that withholds live saving treatments behind a paywall only surmountable with one's life savings and getting insulin nearly for free (as these great men intended) I am very interested in how they not only came up with the treatment, but how doctors in the 1920s managed to stay in agreement to not profit off of the literal lifeline of thousands of people.
@Vertigo6000
@Vertigo6000 6 місяців тому
As someone who was just recently diagnosed with diabetes. This series has taken on a whole new perspective for me. Im so greatful that this discovery was made, and right here in my own country too.
@billybossier2888
@billybossier2888 2 роки тому
We should never forget that then the pharma companies then took over and started charging hundreds of dollars for Insulin.
@AegixDrakan
@AegixDrakan 2 роки тому
Yeah, it's insane and downright evil how much money US pharma companies charge for insulin. Especially if you look up in Canada and see that you can get a bottle up here for under 20 bucks. It does NOT need to be as expensive as it is down south. :(
@arieldahl
@arieldahl 2 роки тому
albeit, a problem that roots in the American medical system... I hope the US will wake up and rework the system but unfortunately, I won't hold my breath.
@dbrokensoul
@dbrokensoul 2 роки тому
Wow. This episode is amazing. That moment when the parent cried is wonderfully written and delivered. I love this series already
@bobpiss3400
@bobpiss3400 2 роки тому
Scientists: agree not to profit off the discovery pharmaceutical companies: *yoink*
@kevindidi6343
@kevindidi6343 2 роки тому
Super proud to see my university (and our most proud contribution) featured in an Extra History! Thanks for the informative video!
@a_pirate1434
@a_pirate1434 2 роки тому
Thank you for doing a series on this- some aspects of history are easily drowned out by talk of kings and generals, yet have had a stunning impact on people’s lives- like this. Had I been diagnosed with T1 Diabetes a century earlier than I did, I would’ve certainly been dead by age 6, but with modern medicine life expectancy for T1 diabetics is approaching parity with non-diabetics. Truly revolutionary.
@johneverett484
@johneverett484 2 роки тому
I was scrolling through my recommend when I saw this video, me and my brother have had type 1 diabetes for a while and I’ve really wanted to learn about the discovery of the thing that is keeping me alive, thank you guys for doing this!
@medeastar
@medeastar 2 роки тому
I'm now not only looking forward to part two, but to the future medical breakthrough episodes Really helps young people nowadays to watch something entertaining, but also educational So from the bottom of my heart, thank you Extra Credits for making History fun for me and my family
@andrewenderfrost8161
@andrewenderfrost8161 2 роки тому
this video dropped right as I got my first continuous glucose monitor prescribed. Remembering my 2 weeks of this made it almost too hard to finish the video, those poor children :/ Thanks Extra Credits team for being so wonderful.
@pentagonofpeople
@pentagonofpeople 2 роки тому
It's great watching this and how intent they were on not profiting from it and then seeing that a month of insulin costs hundreds of dollars
@Ben_306
@Ben_306 2 роки тому
When presented with a dire case of drug pricing, apply the Banting maneuver without delay
@nathanx2000.
@nathanx2000. 2 роки тому
I owe my life to these researchers
@pixelnpc8480
@pixelnpc8480 2 роки тому
This landed right in my feed not but three minutes ago. Good timing there guys!
@thepoglin8479
@thepoglin8479 2 роки тому
man its a good day when extra credits posts a new series
@FlaviusBelisarius-ck6uv
@FlaviusBelisarius-ck6uv 2 роки тому
As a med student, I’ve been waiting for this!
@tomholmes5055
@tomholmes5055 2 роки тому
I've been a Type 1 for 12+ years now. Amazing to see how far we've come in 100 years.
@24dasr
@24dasr 2 роки тому
This was one of the most important scientific discoveries in history and they decided to make this life saving thing cost extremely high amounts of money that most people can't afford to spend
@intermediategamer6871
@intermediategamer6871 2 роки тому
My brother actually has diabetes type 1, so this was a very informational video and I loved it!
@limratanak1716
@limratanak1716 2 роки тому
100 years ago there is a drama that saves millions of lives.
@ryanelliott71698
@ryanelliott71698 2 роки тому
I’m very glad he’s covering this. It really was a game changer.
@alexanderrowley9870
@alexanderrowley9870 2 роки тому
These medical histories have ended up being my favourite stories EH does. From John Snow to JDR's polio drive, they've all been really interesting :)
@cutterlmao
@cutterlmao 2 роки тому
To think that without four people constantly fighting with each other to achieve the same goal, I wouldn’t be here without them. That’s truly amazing, and I’m glad they could do this
@Tyrandir
@Tyrandir 2 роки тому
I've been hoping you guys would do a series on insulin, this makes me so happy! It'll be nice to have an easy and fun way to explain how that loophole mentioned here would come back 100 years later to such disastrous effect. I hope you get the chance to talk a bit about the projects like Open Insulin :D
@Mordeczka1234
@Mordeczka1234 2 роки тому
I love your medicine related videos! Please make more of them!
@davidt1d
@davidt1d 2 роки тому
This series is going to be awesome and it’s so great you said how type 1 and type 2 are different
@colinmunro3158
@colinmunro3158 2 роки тому
It has been said that insulin was the last medical advancement not motivated by profit. Additionally, the development of insulin is a point of great pride among Canadians.
@purpledevilr7463
@purpledevilr7463 2 роки тому
Hopefully the end of this mentions the current patent of insulin and how millions die from not affording it. It’s sold at over a 50X mark up.
@reine_dragon
@reine_dragon 2 роки тому
It's so interesting learning about the people two schools near me are named after. Dr Charles Best secondary and Banting elementary
@IcecreamMcGuy
@IcecreamMcGuy 2 роки тому
Dude I love this video. As always this was such High quality and informative
@romaboo6218
@romaboo6218 2 роки тому
Extra history is my favourite history channel been watching it for like 4 or 5 years now
@TheC0Opper
@TheC0Opper 2 роки тому
I love seeing more being informed about this, as I got Diabetes type 1 at age four. In recent years awareness has grown a lot more but when I was younger I've often gotten either bullied or confused by others that I didn't exercise or diet good enough etc. etc., often stemming from a confusion between type 1 and type 2. The big difference between the two is that type 2 is more becoming resistant to insulin, not having as big of an effect while type 1 is a lack of production of insulin in the body, having to inject it manually. Having more people be aware of this disease others often dismissed as just a joke on obesity, makes me happy that others won't have to endure what I did mentally, while still having to struggle with a chronic disease on top of that.
@alex_zetsu
@alex_zetsu 2 роки тому
So far Macleod might seem like overly skeptic, but in these fields it doesn't hurt to be really sure.
@NYCfrankie
@NYCfrankie 2 роки тому
So happy you guys are doing a story on this my whole family on my dads side struggles with type 2 diabetes and high glucose I've personally been borderline diabetic for 5 or 6 years and have to watch my sugar intake my dad b4 he died though i remember his doctor telling him and me the story about the insanity of insulins creation on a regular visit i took him 2 but nowhere near in depth like this so i find it fascinating can't wait for part 2
@Vigirebs
@Vigirebs 2 роки тому
I’m not usually one for tears but thank you guys. I really hope you can bring some more attention to this with your special touch. A 3 month supply of just one type of insulin can cost 1700 without insurance here in the US Type 1 since 2018
@TheNashNetwork
@TheNashNetwork 2 роки тому
Wow this is a great start to the series. In BC we have high schools named after Banting and Best, and I didn't know they were the doctors behind the discovery of Insulin!
@juhaniheinonen6132
@juhaniheinonen6132 2 роки тому
As a type-1 diabetic it is very cool that you bring up the history of this lifesaving medicine.
@loke6664
@loke6664 2 роки тому
It was certainly one of the most important medical discoveries ever made together with vaccine for polio and smallpox. It is sad that we haven't been able to cure the condition by now though. A friend of mine died this spring 49 years old due to complications of his diabetes and I feel like it is something we should have the competence to cure for good by now. Still, insulin did give my friend 20 years of longer life and many even more. It is a shame the inventors fought so much about one of the most important discoveries in history.
@PaulGAckerman
@PaulGAckerman 2 роки тому
Seeing Death from the Sandman universe was a nice touch. Bravo! And Dr John James Rickard Macleod, his name is my name too.
@JohnnyLodge2
@JohnnyLodge2 2 роки тому
Aww yeah. Multi part science/medicine episodes are the best
@shiftmym9079
@shiftmym9079 2 роки тому
[Gets Spanish flu flashbacks]
@keegandecker4080
@keegandecker4080 2 роки тому
Alright guys listen. I’ve been here since the first Punic war but this was the first time since Flanders fields that an episode of EC has brought me to tears. Those poor children.
@timlamiam
@timlamiam 2 роки тому
As a university of Toronto alumnus, this story makes me beam with pride that I walked the same grounds as these men
@ThisisallMax
@ThisisallMax 2 роки тому
These are some of my favourite EH series!
@cr0ptix888
@cr0ptix888 2 роки тому
Thanks for making this to educate people about diabetes and im honestly tired of explaining it to new people
@cr0ptix888
@cr0ptix888 2 роки тому
I have type 1
@evanulven8249
@evanulven8249 2 роки тому
Scientists and Doctors: "Insulin is such a required substance that we've made it literally cheaper than dirt so everyone that requires it to survive can get it when they need it!" Unbridled murrikan ancap phama corps: "Hhehe literally captive customers have to pay ransom or die." Well-trained apologists: "Ah-ah-ah! Saying that's wrong mean you're a communist!"
@mw5502
@mw5502 2 роки тому
It's not literally cheaper than dirt to produce, but it is fairly cheap to produce. There's a massive markup.
@luska5522
@luska5522 2 роки тому
i get it for free in Brazil. Free Healthcare is great
@SafavidAfsharid3197
@SafavidAfsharid3197 2 роки тому
I doubt evryone who don't agree with American pharma looting it's people are communist like the capitalist pharma companies of india and china would like very much of there cheaper product would get access to American markets and break the monopolies.
@Phhase
@Phhase 2 роки тому
Damn corpos ruin everything. Curses upon them all.
@KasumiRINA
@KasumiRINA 2 роки тому
@@SafavidAfsharid3197 That's the point. People who call those who want America to get better healthcare system "communists" are wrong.
@lordphinix3
@lordphinix3 2 роки тому
As someone who attended Banting High School in the very town where Banting was from I am most interested in this.
@xvang9346
@xvang9346 2 роки тому
A whole series of medical discoveries would be interesting. Some interesting ones would be the first successful surgery of any organ i.e. kidney and heart. Or the discovery of certain medications that revolutionized the way we treat patients today. Excellent video.
@torbjornlekberg7756
@torbjornlekberg7756 2 роки тому
An absurd collection of heroes, but having a sister with type 1 diabetes, I am grateful to them none the less. Oh, and I am once agian so glad that I dont live in the US, where the cost of this life saving medicine is left to the market to set its own prices. My government actually have compassion and integrity enough for making sure my little sister, and anyone in her position within the countrys borders, gets it for free.
@sourabhmayekar3354
@sourabhmayekar3354 2 роки тому
Thank you for the warning of 20 seconds 🙏🏾
@babakkhaleghiborna7027
@babakkhaleghiborna7027 11 місяців тому
As a diabetic who was diagnosed as I was 6, I owe my life health through a pretty easy way to control my situation to these people ❤❤❤
@KuleoRoblox
@KuleoRoblox Рік тому
I love how almost everyone in that research team hated/disliked eachother yet they United for sake of humanity
@quinton1630
@quinton1630 2 роки тому
New extra history video, let’s go!
@zodayn4767
@zodayn4767 2 роки тому
Sounds like this could make a good TV-show with all that drama.
@crimsonghost235
@crimsonghost235 2 роки тому
Banting and best are highly honoured in Canada. An elementary school shared their name, and theres reference to their discoveries on our 100$ bill
@tubanbodyslammer9125
@tubanbodyslammer9125 2 роки тому
This made me tear up. Great story
@timothycarney9652
@timothycarney9652 2 роки тому
It will be interesting to get to the part of the story where we find out what happened between- no patenting any of this and selling the formula for a dollar, to the current insulin prices.
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